Infographic explaining CBD and THC, including main subspecies Indica and Sativa with leaf illustrations. Lists major cannabinoids: CBD, THC, CBN, THCV. Discusses legalities, types of CBD, and emerging problems with delta-8-THC. Features chemical structures and decorative oil dropper bottles.
Infographic titled "Current State of Evidence for CBD-THC". It is divided into two sections: "The Good" and "The Bad". The Good indicates conclusive evidence that cannabis or cannabinoids are effective for chronic pain, chemotherapy-induced nausea, and MS symptoms. Moderate evidence is noted for sleep outcomes and cognitive performance. The Bad notes evidence of associations with schizophrenia, bipolar symptoms, depression, suicidal behavior, anxiety, and cognitive impairment. Cannabis leaves are used as decorative elements.

Click Image to Download

Infographic titled "The Ugly and The Challenge" outlines statistical associations between cannabis use and health issues like motor vehicle crashes and respiratory symptoms. It discusses barriers to cannabis research, including regulatory status, study resources, and funding, with reference to federal restrictions and legal acts. Contains QR code for more information.

REFERENCES:

·  Richtel M.  This drug gets you high and is legal (maybe) across the country. The New York Times; 2021.

·   Kruger, J.S., Kruger, D.J. Delta-8-THC: Delta-9-THC’s nicer younger sibling? J Cannabis Res 4, 4 (2022). https://doi.org/10.1186/s42238-021-00115-8.

·    Spindle TR, Sholler DJ, Cone EJ, et al. Cannabinoid Content and Label Accuracy of Hemp-Derived Topical Products Available Online and at National Retail Stores. JAMA Netw Open. 2022;5(7):e2223019. doi:10.1001/jamanetworkopen.2022.23019.

·     Bonn-Miller MO, Loflin MJE, Thomas BF, Marcu JP, Hyke T, Vandrey R. Labeling Accuracy of Cannabidiol Extracts Sold Online. JAMA. 2017;318(17):1708–1709. doi:10.1001/jama.2017.11909

·     https://www.fda.gov/consumers/consumer-updates/5-things-know-about-delta-8-tetrahydrocannabinol-delta-8-thc

·     https://emergency.cdc.gov/han/2021/han00451.asp

·     The Health Effects of Cannabis and Cannabinoids: The Current State of Evidence and Recommendations for Research. National Academies of Sciences, Engineering, and Medicine; Health and Medicine Division; Board on Population Health and Public Health Practice; Committee on the Health Effects of Marijuana: An Evidence Review and Research Agenda. Washington (DC): National Academies Press (US); 2017 Jan 12.

·     Ziva D Cooper, PhD, Donald I Abrams, MD, Steven Gust, PhD, Alejandro Salicrup, PhD, Douglas C Throckmorton, MD, Challenges for Clinical Cannabis and Cannabinoid Research in the United States, JNCI Monographs, Volume 2021, Issue 58, December 2021, Pages 114–122, https://doi.org/10.1093/jncimonographs/lgab009

·     Pollio A. The Name of Cannabis: A Short Guide for Nonbotanists. Cannabis Cannabinoid Res. 2016;1(1):234-238. doi:10.1089/can.2016.0027.

·     Shannon S, Lewis N, Lee H, Hughes S. Cannabidiol in Anxiety and Sleep: A Large Case Series. Perm J. 2019;23:18-041. doi:10.7812/TPP/18-041